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1

Invited review: Architectures and mechanisms of ATP binding cassette proteins

Hopfner, Karl-Peter

Journal:

Year:

2016

Language:

english

File:

PDF, 899 KB

english, 2016

2

Swi2/Snf2 remodelers: hybrid views on hybrid molecular machines

Karl-Peter Hopfner, Christian-Benedikt Gerhold, Kristina Lakomek, Petra Wollmann

Journal:

Current Opinion in Structural Biology

Year:

2012

Language:

english

File:

PDF, 2.24 MB

english, 2012

3

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Ablasser, Andrea, Goldeck, Marion, Cavlar, Taner, Deimling, Tobias, Witte, Gregor, Röhl, Ingo, Hopfner, Karl-Peter, Ludwig, Janos, Hornung, Veit

Journal:

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

4

New Enzyme Lineages by Subdomain Shuffling

Karl-Peter Hopfner, Erhard Kopetzki, Georg-Burkhard Kree, Wolfram Bode, Robert Huber and Richard A. Engh

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.73 MB

english, 1998

5

Structural basis of the (in)activity of the apical DNA damage response kinases ATM, ATR and DNA-PKcs

Jansma, Marijke, Hopfner, Karl-Peter

Journal:

Progress in Biophysics and Molecular Biology

Year:

2020

File:

PDF, 2.04 MB

2020

6

Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain

Julia J. Griese, Karl-Peter Hopfner

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

7

MRE11/RAD50/NBS1: complex activities

Nora Assenmacher, Karl-Peter Hopfner

Journal:

Year:

2004

Language:

english

File:

PDF, 450 KB

english, 2004

8

The exosome: a macromolecular cage for controlled RNA degradation

Katharina Büttner, Katja Wenig, Karl-Peter Hopfner

Journal:

Molecular Microbiology

Year:

2006

Language:

english

File:

PDF, 302 KB

english, 2006

9

The ternary microplasmin–staphylokinase–microplasmin complex is a proteinase–cofactor–substrate complex in action

Parry, Marina A. A., Fernandez-Catalan, Carlos, Bergner, Andreas, Huber, Robert, Hopfner, Karl-Peter, Schlott, Bernhard, Gührs, Karl-Heinz, Bode, Wolfram

Journal:

Natural Structural Biology

Year:

1998

Language:

english

File:

PDF, 3.64 MB

english, 1998

10

Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin

Fenn, Sebastian, Breitsprecher, Dennis, Gerhold, Christian B, Witte, Gregor, Faix, Jan, Hopfner, Karl-Peter

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 3.14 MB

english, 2011

11

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

Hopfner, Karl-Peter, Craig, Lisa, Moncalian, Gabriel, Zinkel, Robert A., Usui, Takehiko, Owen, Barbara A. L., Karcher, Annette, Henderson, Brendan, Bodmer, Jean-Luc, McMurray, Cynthia T.

Journal:

Year:

2002

Language:

english

File:

PDF, 441 KB

english, 2002

12

Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II

Schwarz, Klaus, Iolascon, Achille, Verissimo, Fatima, Trede, Nikolaus S, Horsley, Wyatt, Chen, Wen, Paw, Barry H, Hopfner, Karl-Peter, Holzmann, Karlheinz, Russo, Roberta

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 385 KB

english, 2009

13

Structural basis for DNA duplex separation by a superfamily-2 helicase

Büttner, Katharina, Nehring, Sebastian, Hopfner, Karl-Peter

Journal:

Nature Structural and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 535 KB

english, 2007

14

Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

Pannicke, Ulrich, Ma, Yunmei, Hopfner, Karl-Peter, Niewolik, Doris, Lieber, Michael R, Schwarz, Klaus

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 309 KB

english, 2004

15

MlaA, a hexameric ATPase linked to the Mre11 complex in archaeal genomes

Manzan, Angelo, Pfeiffer, Günter, Hefferin, Melissa L, Lang, Cara E, Carney, James P, Hopfner, Karl-Peter

Journal:

Year:

2004

Language:

english

File:

PDF, 195 KB

english, 2004

16

The exosome, plugged

Hartung, Sophia, Hopfner, Karl-Peter

Journal:

Year:

2007

Language:

english

File:

PDF, 125 KB

english, 2007

17

Dihydrofolate Reductase Deficiency Due to a Homozygous DHFR Mutation Causes Megaloblastic Anemia and Cerebral Folate Deficiency Leading to Severe Neurologic Disease

Holger Cario, Desirée E.C. Smith, Henk Blom, Nenad Blau, Harald Bode, Karlheinz Holzmann, Ulrich Pannicke, Karl-Peter Hopfner, Eva-Maria Rump, Zuleya Ayric, Elisabeth Kohne, Klaus-Michael Debatin, Yvo

Journal:

The American Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

18

Chromosome Cohesion: Closing Time

Karl-Peter Hopfner

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 60 KB

english, 2003

19

Structural Biochemistry of ATP-Driven Dimerization and DNA-Stimulated Activation of SMC ATPases

Alfred Lammens, Alexandra Schele, Karl-Peter Hopfner

Journal:

Current Biology

Year:

2004

Language:

english

File:

PDF, 290 KB

english, 2004

20

Chromosome Biology: The Crux of the Ring

Frank Uhlmann, Karl-Peter Hopfner

Journal:

Current Biology

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

21

Sensing of viral nucleic acids by RIG-I: From translocation to translation

Andreas Schmidt, Simon Rothenfusser, Karl-Peter Hopfner

Journal:

European Journal of Cell Biology

Year:

2012

Language:

english

File:

PDF, 794 KB

english, 2012

22

Mechanisms of nucleic acid translocases: lessons from structural biology and single-molecule biophysics

Karl-Peter Hopfner, Jens Michaelis

Journal:

Current Opinion in Structural Biology

Year:

2007

Language:

english

File:

PDF, 771 KB

english, 2007

23

X-Ray Structure of RLI, an Essential Twin Cassette ABC ATPase Involved in Ribosome Biogenesis and HIV Capsid Assembly

Annette Karcher, Katharina Bu¨ttner, Birgit Märtens, Ralf-Peter Jansen, Karl-Peter Hopfner

Journal:

Year:

2005

Language:

english

File:

PDF, 970 KB

english, 2005

24

DNA double-strand break repair from head to tail

Karl-Peter Hopfner, Christopher D Putnam, John A Tainer

Journal:

Current Opinion in Structural Biology

Year:

2002

Language:

english

File:

PDF, 388 KB

english, 2002

25

Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures

Karl-Peter Hopfner, John A Tainer

Journal:

Current Opinion in Structural Biology

Year:

2003

Language:

english

File:

PDF, 665 KB

english, 2003

26

DNA Mismatch Repair: The Hands of a Genome Guardian

Karl-Peter Hopfner, John A Tainer

Journal:

Year:

2000

Language:

english

File:

PDF, 401 KB

english, 2000

27

Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding

Karl-Peter Hopfner, Anja Lang, Annette Karcher, Katrin Sichler, Erhard Kopetzki, Hans Brandstetter, Robert Huber, Wolfram Bode, Richard A Engh

Journal:

Year:

1999

Language:

english

File:

PDF, 217 KB

english, 1999

28

X-Ray Structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase Core and Its Complex with DNA

Harald Dürr, Christian Körner, Marisa Müller, Volker Hickmann, Karl-Peter Hopfner

Journal:

Year:

2005

Language:

english

File:

PDF, 790 KB

english, 2005

29

DNA Double-Strand Breaks Come into Focus

Karl-Peter Hopfner

Journal:

Year:

2009

Language:

english

File:

PDF, 515 KB

english, 2009

30

Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

Dominikus Strasser, Konstantin Neumann, Hanna Bergmann, Mohlopheni J. Marakalala, Reto Guler, Anna Rojowska, Karl-Peter Hopfner, Frank Brombacher, Henning Urlaub, Gottfried Baier, Gordon D. Brown, Mic

Journal:

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

31

The Rad50 Signature Motif: Essential to ATP Binding and Biological Function

Gabriel Moncalian, Bettina Lengsfeld, Venugopal Bhaskara, Karl-Peter Hopfner, Annette Karcher, Erinn Alden, John A. Tainer, Tanya T. Paull

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 2.65 MB

english, 2004

32

Differential Arrangements of Conserved Building Blocks among Homologs of the Rad50/Mre11 DNA Repair Protein Complex

Martijn de Jager, Kelly M. Trujillo, Patrick Sung, Karl-Peter Hopfner, James P. Carney, John A. Tainer, John C. Connelly, David R.F. Leach, Roland Kanaar, Claire Wyman

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 4.05 MB

english, 2004

33

Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs

Nora Assenmacher, Katja Wenig, Alfred Lammens, Karl-Peter Hopfner

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 655 KB

english, 2006

34

Structural Basis for Adenylate Kinase Activity in ABC ATPases

Alfred Lammens, Karl-Peter Hopfner

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

35

Structural Framework for the Mechanism of Archaeal Exosomes in RNA Processing

Katharina Büttner, Katja Wenig, Karl-Peter Hopfner

Journal:

Year:

2005

Language:

english

File:

PDF, 1009 KB

english, 2005

36

Establishment of Sister Chromatid Cohesion at the S. cerevisiae Replication Fork

Armelle Lengronne, John McIntyre, Yuki Katou, Yutaka Kanoh, Karl-Peter Hopfner, Katsuhiko Shirahige, Frank Uhlmann

Journal:

Year:

2006

Language:

english

File:

PDF, 1.17 MB

english, 2006

37

The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I

Sheng Cui, Katharina Eisenächer, Axel Kirchhofer, Krzysztof Brzózka, Alfred Lammens, Katja Lammens, Takashi Fujita, Karl-Klaus Conzelmann, Anne Krug, Karl-Peter Hopfner

Journal:

Year:

2008

Language:

english

File:

PDF, 1.42 MB

english, 2008

38

Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates

Gregor Witte, Sophia Hartung, Katharina Büttner, Karl-Peter Hopfner

Journal:

Year:

2008

Language:

english

File:

PDF, 2.05 MB

english, 2008

39

The influence of residue 190 in the S1 site of trypsin-like serine proteases on substrate selectivity is universally conserved

Katrin Sichler, Karl-Peter Hopfner, Erhard Kopetzki, Robert Huber, Wolfram Bode, Hans Brandstetter

Journal:

Year:

2002

Language:

english

File:

PDF, 87 KB

english, 2002

40

Dramatic enhancement of the catalytic activity of coagulation factor IXa by alcohols

Jörg Stürzebecher, Erhard Kopetzki, Wolfram Bode, Karl-Peter Hopfner

Journal:

Year:

1997

Language:

english

File:

PDF, 611 KB

english, 1997

41

Crystal Structures of Uninhibited Factor VIIa Link its Cofactor and Substrate-assisted Activation to Specific Interactions

Katrin Sichler, David W. Banner, Allan D'Arcy, Karl-Peter Hopfner, Robert Huber, Wolfram Bode, Georg-Burkhard Kresse, Erhard Kopetzki, Hans Brandstetter

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 2.63 MB

english, 2002

42

Structural Biology of Rad50 ATPase: ATP-Driven Conformational Control in DNA Double-Strand Break Repair and the ABC-ATPase Superfamily

Karl-Peter Hopfner, Annette Karcher, David S. Shin, Lisa Craig, L.Matthew Arthur, James P. Carney, John A. Tainer

Journal:

Year:

2000

Language:

english

File:

PDF, 742 KB

english, 2000

43

Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase

Karl-Peter Hopfner, Annette Karcher, Lisa Craig, Tammy T. Woo, James P. Carney, John A. Tainer

Journal:

Year:

2001

Language:

english

File:

PDF, 2.92 MB

english, 2001

44

Correlating Calcium Binding, Förster Resonance Energy Transfer, and Conformational Change in the Biosensor TN-XXL

Geiger, Anselm, Russo, Luigi, Gensch, Thomas, Thestrup, Thomas, Becker, Stefan, Hopfner, Karl-Peter, Griesinger, Christian, Witte, Gregor, Griesbeck, Oliver

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 966 KB

english, 2012

45

Species-specific detection of the antiviral small-molecule compound CMA by STING

Cavlar, Taner, Deimling, Tobias, Ablasser, Andrea, Hopfner, Karl-Peter, Hornung, Veit

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 990 KB

english, 2013

46

Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties

Klein, Christian, Lammens, Alfred, Schäfer, Wolfgang, Georges, Guy, Schwaiger, Manfred, Mössner, Ekkehard, Hopfner, Karl-Peter, Umaña, Pablo, Niederfellner, Gerhard

Journal:

Year:

2013

Language:

english

File:

PDF, 2.91 MB

english, 2013

47

Structural mechanism of cytosolic DNA sensing by cGAS

Civril, Filiz, Deimling, Tobias, de Oliveira Mann, Carina C., Ablasser, Andrea, Moldt, Manuela, Witte, Gregor, Hornung, Veit, Hopfner, Karl-Peter

Journal:

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

48

NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2

Braciak, Todd A, Wildenhain, Sarah, Roskopf, Claudia C, Schubert, Ingo A, Fey, Georg H, Jacob, Uwe, Hopfner, Karl-Peter, Oduncu, Fuat S

Journal:

Journal of Translational Medicine

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

49

Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses

Liang, Qiming, Seo, Gil Ju, Choi, Youn Jung, Kwak, Mi-Jeong, Ge, Jianning, Rodgers, Mary A., Shi, Mude, Leslie, Benjamin J., Hopfner, Karl-Peter, Ha, Taekjip, Oh, Byung-Ha, Jung, Jae U.

Journal:

Cell Host & Microbe

Year:

2014

Language:

english

File:

PDF, 1.74 MB

english, 2014

50

Editorial overview: Theory and simulation: Macromolecular machines

Hopfner, Karl-Peter, Smith, Thomas J

Journal:

Current Opinion in Structural Biology

Year:

2014

Language:

english

File:

PDF, 131 KB

english, 2014